Physiologically relevant media are associated with overlapping metabolic responses in primary human hepatocytes and Huh7 cells
Eloise Cross, Felix Westcott, K H Smith, Shilpa R. Nagarajan, Fabio Sanna, Kaitlyn M.J.H. Dennis, Leanne Hodson
This study compares metabolic responses of primary human hepatocytes and Huh7 cells cultured in physiologically-relevant fatty acid mixtures, finding similar lipid composition and metabolic profiles despite differences in viability and gene expression.
Physiological Reports · Jul 1, 2026Peer-reviewedCell Biology