Identification of reduced host transcriptomic signatures for tuberculosis and digital PCR-based validation and quantification
Harriet D. Gliddon, Myrsini Kaforou, Mary Alikian, Dominic Habgood-Coote, Chenxi Zhou, Tolu Oni, Suzanne T. B. Anderson, Andrew Brent, Amelia Catharine Crampin, Brian Eley, Robert S. Heyderman, Florian Kern, Paul Richard Langford, Tom H. M. Ottenhoff, Martin Lloyd Hibberd, , Michael Levin
The paper identifies reduced host transcriptomic signatures for tuberculosis using microarray data and validates them with digital PCR, showing high accuracy in distinguishing TB from other conditions and latent TB.
Frontiers in Immunology · Mar 1, 2021Peer-reviewedMolecular Biology