Michael Levin

The paper trains dissociated rat cortical cultures to control network burst initiation and error recovery over days using a closed-loop system, showing retention and consolidation of learned behaviors.

This study examines how limb regeneration in Xenopus laevis affects brain and amputation-site gene expression, identifying changes in metabolic and immune pathways and cross-species similarities in regenerative responses.

Antibiotic treatment of meningococcal and other sepsis causative bacteria triggers the release of histone-like proteins (HLPs) that damage the endothelium and drive coagulopathy, but these effects can be neutralized by non-anticoagulant heparins or anti-HLP antibodies.

This study identifies genetic loci associated with pneumococcal carriage in children through a genome-wide association analysis.

The paper integrates multi-omics data from pediatric sepsis patients to identify a reproducible inflammatory host-response axis associated with disease severity.

This study investigates how synthetic living constructs, specifically Xenobots, sense and store memory through transcriptional and physiological changes after exposure to chemical stimuli.

This study stratifies Kawasaki Disease patients using transcriptomic and proteomic profiles, finding KD responses resemble bacterial infections but with distinct features suggesting alternative triggers.

The paper identifies reduced host transcriptomic signatures for tuberculosis using microarray data and validates them with digital PCR, showing high accuracy in distinguishing TB from other conditions and latent TB.

This study identifies distinct lipidomic changes in febrile children with bacterial vs. viral infections, showing potential for metabolic biomarkers to aid in clinical diagnosis.

This study uses dual transcriptome analysis to identify host and parasite gene expression associated with severe malaria in Gambian children, showing parasite load explains most human gene expression differences but only a third of parasite gene differences.

The paper estimates parasite load dynamics in malaria to identify host resistance mechanisms, finding novel roles for proteases and detrimental effects of interferon response.