Human Rhinovirus 16 impacts cilia structure in 3D cultured primary bronchial epithelial tissue through alternative splicing of host cilia RNAs.
Christoforos Rozario, Quan Gu, Andrew Stevenson, Rose A. Maciewicz, Sheila V. Graham
This study shows HRV16 infection alters host cilia structure via alternative splicing of cilia RNAs, mediated by SRPK1 regulation.
bioRxiv · Aug 26, 2025 · PreprintMicrobiology