Author

Sheila V. Graham

MRC University of Glasgow Centre for Virus ResearchORCID 0000-0002-7140-8279Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Sheila V. Graham1 paper

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrew StevensoniD· 2 shared Quan GuiD· 2 shared Arwa A. FaizoiD· 1 shared Christoforos RozarioiD· 1 shared Clare Bellward· 1 shared Hegel R. Hernandez-LopeziD· 1 shared Rose A. MaciewicziD· 1 shared

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2025-2025 · peak 2/yr

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7 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

Andrew StevensonORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 26, 2025

Human Rhinovirus 16 impacts cilia structure in 3D cultured primary bronchial epithelial tissue through alternative splicing of host cilia RNAs.

Christoforos Rozario, Quan Gu, Andrew Stevenson…·Sheila V. Graham

This study shows HRV16 infection alters host cilia structure via alternative splicing of cilia RNAs, mediated by SRPK1 regulation.

DOI 10.1101/2025.08.26.672366

humanbulk RNA-seq

𝕏 PostBluesky

MicrobiologyPLoS PathogensPeer-reviewedApr 9, 2025

The splicing factor kinase, SR protein kinase 1 (SRPK1) is essential for late events in the human papillomavirus life cycle.

Arwa A. Faizo, Clare Bellward, Hegel R. Hernandez-Lopez…·Sheila V. Graham

This study shows that SRPK1 inhibition with SRPIN340 blocks HPV16 late gene expression and restores epithelial barrier and immune function by affecting splicing and gene expression.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky