Levi P. Sowers

Inhibition of Posterior Thalamic Nuclei Attenuates CGRP-induced Migraine-like Behavior in Mice

This study shows that inhibiting the posterior thalamic nuclei in mice reduces CGRP-induced touch hypersensitivity and partially reduces light aversion, suggesting the PoT's role in migraine-like behaviors.

CGRP Administration into the Cerebellum Evokes Migraine-like Behaviors Predominately in Female Mice

This study shows that CGRP injection into the cerebellar medial nuclei induces migraine-like behaviors in mice, with female mice showing additional anxiety, tactile hypersensitivity, and pain responses.

Female mice exhibit a more sensitive automated squint response to pain induced by CGRP and amylin

The paper develops an automated squint assay to measure pain in mice, showing female mice have a more sensitive response to CGRP and amylin than males.

PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP

This study shows PACAP induces light aversion in mice independently of CGRP, with inheritable responder and nonresponder phenotypes and distinct gene expression patterns.

Multifactorial and closed head impact traumatic brain injuries cause distinct tactile hypersensitivity profiles

This study characterizes two models of post-traumatic headache, showing distinct tactile hypersensitivity profiles and highlighting the role of CGRP in persistent hypersensitivity.