Thomas L. Duong

Glymphatic function restored by α1-noradrenergic antagonism alleviates headache allodynia in mice

This study shows that prazosin, an α1-noradrenergic antagonist, restores glymphatic function and reduces facial allodynia in mice with migraine-like symptoms.

Inhibition of Posterior Thalamic Nuclei Attenuates CGRP-induced Migraine-like Behavior in Mice

This study shows that inhibiting the posterior thalamic nuclei in mice reduces CGRP-induced touch hypersensitivity and partially reduces light aversion, suggesting the PoT's role in migraine-like behaviors.

CGRP Administration into the Cerebellum Evokes Migraine-like Behaviors Predominately in Female Mice

This study shows that CGRP injection into the cerebellar medial nuclei induces migraine-like behaviors in mice, with female mice showing additional anxiety, tactile hypersensitivity, and pain responses.