Mapping Cell Fate Transition in Space and Time
Yichen Gu, Jialin Liu, Kun Hee Lee, Chen Li, Lu Lu, Jaimee Moline, Renxiang Guan, Joshua D. Welch
This paper introduces TopoVelo, a method to infer spatial and temporal dynamics of cell fate transitions from spatial transcriptomic data, improving spatial coherence and accuracy in cell differentiation and migration analysis.
Nature Biotechnology · Jul 16, 2025Peer-reviewedBioinformatics