Chen Li

This study identifies GFI1 as a key regulator of HIV latency in hematopoietic progenitors through transcriptomic analysis and functional assays.

This study examines HPV integration in HNSCC using RNA-seq data to link splicing events and expression ratios to poor clinical outcomes.

This paper introduces TopoVelo, a method to infer spatial and temporal dynamics of cell fate transitions from spatial transcriptomic data, improving spatial coherence and accuracy in cell differentiation and migration analysis.

CytoSimplex visualizes cell differentiation trajectories using simplex geometry to represent cell fate commitment and potential in 2D and 3D plots.

DeepMosaic detects mosaic single nucleotide variants without control samples using deep convolutional neural networks, achieving high accuracy and uncovering many variants missed by existing methods.

The paper introduces hECA, a cell-centric human Ensemble Cell Atlas, which integrates scRNA-seq data from multiple studies to enable targeted data retrieval, multi-view presentations, and customizable reference creation for cell type annotations.

The paper introduces MultiVelo, a model that integrates epigenomic and transcriptomic data to infer dynamic gene regulation and cell fate prediction.