Author

Brea Tinsley

Columbia University Irving Medical CenterORCID 0000-0002-5404-5832Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Brea Tinsley1 paper · Youngstown State University

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Amesh K. Sarecha· 1 shared Heena AgarwaliD· 1 shared John A. Zadroga· 1 shared Lale ÖzcaniD· 1 shared Stefano Spolitu· 1 shared Yating WangiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperMolecular Biology

Amesh K. Sarecha

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1 paper

Recent·Most cited

Geranylgeranyl Isoprenoids and Hepatic Rap1a Regulate Basal and Statin-Induced Expression of PCSK9

Yating Wang, Brea Tinsley, Stefano Spolitu, John A. Zadroga, Heena Agarwal, Amesh K. Sarecha, Lale Özcan

This study identifies geranylgeranyl isoprenoids and hepatic Rap1a as regulators of PCSK9 expression, showing that statin-induced PCSK9 is dependent on these factors and their inhibition reduces PCSK9 and plasma cholesterol.

Journal of Lipid Research · Feb 2, 2024Peer-reviewedMolecular Biology