BioinformaticsComputational and Structural Biotechnology JournalPeer-reviewed
Mapping the Energy Landscape of PROTAC-Mediated Protein-protein Interactions
José A. Villegas, Tasneem M. Vaid, Michael E. Johnson, Terry W. Moore
The paper develops a method to restrict the search space for PROTAC-mediated protein-protein interactions using a cyclic coordinate descent algorithm, showing the global minimum corresponds to native-like conformations.
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