NeurosciencebioRxivPreprint
Transcriptional Profiling of D1-MSNs Reveals SIRT1-Dependent and -Independent Responses to Chronic Social Defeat Stress
Hee‐Dae Kim, H. Cho, Angel Nguyen…·Deveroux Ferguson
This study uses cell-type-specific transcriptomics to show that SIRT1 modulates depression susceptibility in D1-MSNs through metabolic and circadian pathways under chronic social defeat stress.
DOI 10.1101/2025.11.03.686384