Vaidotas Kiseliovas

Decipher is a deep generative model that integrates single-cell RNA-seq data to visualize and characterize transitions between normal and perturbed cell states across different diseases.

The paper introduces inDrops-2, a cost-efficient scRNA-seq platform that profiles clinical samples with sensitivity comparable to commercial systems and demonstrates its utility in analyzing lung carcinoma samples.

Palantir models cell fate as a probabilistic process using entropy to analyze differentiation trajectories in human hematopoiesis, identifying key transcription factors and terminal states.