Simonas Juzėnas

NinjaSeq: programmable restriction enzyme-based sequencing library preparation with random access for DNA data storage

NinjaSeq replaces conventional end-repair/dA-tailing with restriction enzymes for nanopore sequencing, enabling random access and improved decoding accuracy.

High-throughput single cell -omics using semi-permeable capsules

This paper introduces a semi-permeable capsule technology for high-throughput single-cell -omics, demonstrating its utility in scRNA-Seq of hematopoietic disorders and uncovering transcriptome changes in AML.

High Performance protocol for ultra-short DNA sequencing using Oxford Nanopore Technology (ONT)

The paper presents an optimized protocol for sequencing ultra-short DNA fragments using Oxford Nanopore Technology, improving data quality compared to standard protocols.

inDrops-2: a flexible, versatile and cost-efficient droplet microfluidics approach for high-throughput scRNA-seq of fresh and preserved clinical samples

The paper introduces inDrops-2, a cost-efficient scRNA-seq platform that profiles clinical samples with sensitivity comparable to commercial systems and demonstrates its utility in analyzing lung carcinoma samples.

New susceptibility loci for severe COVID-19 by detailed GWAS analysis in European populations

This study identifies a new susceptibility locus for severe COVID-19 through a detailed GWAS analysis in European populations, focusing on genetic variants associated with disease severity.

Genome-wide analysis of 944,133 individuals provides insights into the etiology of hemorrhoidal disease

This study performs a genome-wide association analysis of hemorrhoidal disease in 944,133 individuals, identifying 102 risk loci and linking them to vascular and tissue development pathways.

Trans-ethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals shared but also ethnicity-specific disease associations

This study identifies shared and ethnicity-specific HLA associations with ulcerative colitis through trans-ethnic analysis of diverse populations.

Depletion of erythropoietic miR-486-5p and miR-451a improves detectability of rare microRNAs in peripheral blood-derived small RNA sequencing libraries

The paper presents a method to deplete dominant miRNAs from blood-derived RNA samples, improving detectability of low-abundance miRNAs in small RNA sequencing.