Andreas H. Kottmann

This study shows that removing dopamine 2 receptors from cholinergic neurons reduces L-DOPA-induced dyskinesias while maintaining its therapeutic benefits.

This study shows that ACE2 in the dorsolateral striatum regulates the coordination of acetylcholine and dopamine, affecting motor learning and movement.

This paper shows that Smoothened on cholinergic interneurons modulates acetylcholine dynamics and dopamine coordination, affecting motor learning.

The paper shows that sequential Shh expression by ventricular zone derivatives regulates oligodendrocyte precursor populations and spinal cord scaling.

The paper shows that reduced ventral oligodendrocyte precursor cells lead to increased dorsal OPCs with abnormal morphology and function in the spinal cord.

This study shows that enhancing sonic hedgehog signaling reduces L-Dopa-induced dyskinesia in Parkinson's models by targeting dopamine neurons and cholinergic interneurons.