Persistent low-level variants in a subset of HCMV genes are highly predictive of poor outcome in immunocompromised patients with cytomegalovirus infection
Cristina Venturini, Julia Colston, Oscar J. Charles, Timothy Best, Claire E. Atkinson, Calum Forrest, Charlotte A. Williams, Kanchan Rao, Austen J. J. Worth, Douglas Thorburn, Mark A Harber, P. D. Griffiths, Judith Breuer
The paper identifies a viral signature from HCMV genes associated with poor outcomes in immunocompromised patients, using deep sequencing and machine learning.
medRxiv · Sep 12, 2022 · PreprintGenetic & Genomic Medicine