Author

Hervé Dombret

Assistance Publique – Hôpitaux de ParisORCID 0000-0002-5454-6768Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Claude PreudhommeiD· 2 shared Abrar AlharbiiD· 1 shared Adam Ivey· 1 shared Alan K. BurnettiD· 1 shared Alyssa Clay‐GilmouriD· 1 shared Amanda GilkesiD· 1 shared András MassziiD· 1 shared André BarucheliD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioinformatics

Claude PreudhommeORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 16, 2026

In vivo isogenic modelling unveils TP53-associated relapse trajectories in T-cell acute lymphoblastic leukemia

Stéphanie Gachet, Samuel Quentin, Lucie Hernandez…·Jean Soulier

This study uses patient-derived xenografts to identify TP53-associated relapse mechanisms in T-ALL, showing relapse phenotypes linked to OXPHOS metabolism and MYC signaling.

DOI 10.64898/2026.01.19.700255

humanbulk RNA-seq

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BioinformaticsBMC BioinformaticsPeer-reviewedOct 28, 2022

Frugal alignment-free identification of FLT3-internal tandem duplications with FiLT3r

Augustin Boudry, Sasha Darmon, Nicolas Duployez…·Mikaël Salson

FiLT3r is an alignment-free algorithm that accurately detects FLT3-ITDs in HTS data with high precision and low resource usage.

25 citations

humanwhole-exome sequencing

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Genetic & Genomic MedicineNature CommunicationsPeer-reviewedOct 29, 2021

Genome-wide association study identifies susceptibility loci for acute myeloid leukemia

Wei‐Yu Lin, Sarah Elizabeth Fordham, Eric A. Hungate…·James M. Allan

This study identifies two genome-wide significant susceptibility loci for acute myeloid leukemia through a meta-analysis of GWAS data.

44 citations

humanGWAS summary statistics

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