Author

Jean Soulier

Centre National de la Recherche ScientifiqueORCID 0000-0002-8734-5356Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Emmanuelle ClappieriD· 2 shared André BarucheliD· 1 shared François Sigaux· 1 shared Frank SpelemaniD· 1 shared Hervé DombretiD· 1 shared Hugo BergugnatiD· 1 shared Hugues de ThéiD· 1 shared Jo VandesompeleiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Emmanuelle ClappierORCID

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2 papers

Recent·Most cited

In vivo isogenic modelling unveils TP53-associated relapse trajectories in T-cell acute lymphoblastic leukemia

Stéphanie Gachet, Samuel Quentin, Lucie Hernandez, Loïc Maillard, Marie Passet, Rathana Kim, Hugo Bergugnat, Melha Benlebna, Remy Jelin, Marine Aglave, Maxime Boy, Véronique Parietti, Pierre Fenaux, André Baruchel, Hervé Dombret, , Jean Soulier

This study uses patient-derived xenografts to identify TP53-associated relapse mechanisms in T-ALL, showing relapse phenotypes linked to OXPHOS metabolism and MYC signaling.

bioRxiv · Mar 16, 2026 · PreprintCancer Biology

A comprehensive dataset of TLX1 positive ALL-SIL lymphoblasts and primary T-cell acute lymphoblastic leukemias

Karen Verboom, Wouter Van Loocke, Emmanuelle Clappier, Jean Soulier, Jo Vandesompele, Frank Speleman, Kaat Durinck

The paper presents a comprehensive dataset of TLX1 positive ALL-SIL lymphoblasts and primary T-ALL leukemias using polyA[+] and total RNA sequencing, ATAC sequencing, and ChIP sequencing, validated for quality and biological relevance.

bioRxiv · Jul 8, 2019 · PreprintMolecular Biology