Séverine Padiolleau‐Lefèvre

Design of DNA Aptamers for Lyme disease Diagnosis Combining experimental and numerical approaches

The paper designs DNA aptamers for Lyme disease detection by combining in silico selection using a Restricted Boltzmann Machine with experimental validation of selected sequences.

Predicting single-stranded DNA oligonucleotides 3D structures: an open issue

This paper evaluates three RNA 3D structure prediction tools on a dataset of ssDNA structures to assess their applicability to ssDNA and identify limitations in predicting complex motifs.

Selection and characterization of DNA aptamers targeting the surface borrelial protein CspZ with high-throughput cross-over SELEX

This paper selects and characterizes DNA aptamers targeting the Borrelia surface protein CspZ using cross-over SELEX and validates their binding affinity and specificity.