The safety and efficacy of Ultrasound Histotripsy and human pluripotent stem cell-derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: assessment in an immunocompetent rodent model.
Hassan Rashidi, Amjad Khalil, Saied Froghi, Andrew Rennie Hall, Pierre Gélat, Brian Ritchie Davidson, Alberto Quaglia, Nader Saffari
This study evaluates the safety and feasibility of combining ultrasound histotripsy with liver organoid implantation in rodents to treat congenital metabolic liver disease.
Cell Transplantation · Jul 20, 2025Peer-reviewedBioengineering