Brian Ritchie Davidson

Real time evaluation of the liver microcirculation by whole organ machine perfusion within an MRI system

This study demonstrates the use of MRI to evaluate liver microcirculation during machine perfusion, showing improved preservation and quantitative vascular analysis.

Human hepatic stellate cells orchestrate the accumulation and function of CD103+ tissue-resident CD8+ T-cells in liver fibrosis

Splenic granulopoiesis and S100A9 drive resistance to checkpoint inhibitors conferred by liver metastases

This study shows liver metastases reduce checkpoint inhibitor efficacy by increasing splenic granulopoiesis and S100A9hi neutrophils, which suppress T-cell responses, and demonstrates that targeting S100A9 restores efficacy.

Tube2FEM: a general-purpose highly-automated pipeline for flow related processes in (embedded) tubular objects

This paper introduces a highly-automated pipeline for generating simulation-ready meshes of tubular structures, enabling CFD simulations across various biomedical and industrial applications.

The safety and efficacy of Ultrasound Histotripsy and human pluripotent stem cell-derived hepatic spheroid implantation as a potential therapy for treatment of congenital metabolic liver disease: assessment in an immunocompetent rodent model.

This study evaluates the safety and feasibility of combining ultrasound histotripsy with liver organoid implantation in rodents to treat congenital metabolic liver disease.

Organ-specific isolation of hepatocyte extracellular vesicles from human plasma enables tissue-resolved proteomic and miRNA profiling

The paper develops NEXPLOR, a method to isolate hepatocyte-derived extracellular vesicles from plasma, enabling tissue-resolved proteomic and miRNA profiling for liver disease analysis.