A Systems-Level Framework For Drug Discovery Identifies Csf1R As A Novel Anti-Epileptic Drug Target
Prashant Kumar Srivastava, Jonathan M. van Eyll, Patrice Godard, Manuela Mazzuferi, Bénédicte Danis, Catherine Vandenplas, Patrik Foerch, Karine Leclercq, Georges Mairet‐Coello, Frederic Vanclef, Kirill Shkura, Liisi Laaniste, Andrée Delahaye‐Duriez, Rafal Marian Kaminski, Enrico G. Petretto, Michael R. Johnson
This paper introduces CRAFT, a computational framework for drug target identification, and validates Csf1R as a novel anti-epileptic target using pre-clinical models.
bioRxiv · May 22, 2017 · PreprintSystems Biology