Author

Lizette Zavala

University of ChicagoORCID 0000-0002-5526-3081Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Cassandra K. HayneiD· 1 shared Magdalena SobieńiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBiochemistry

Cassandra K. HayneORCID

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1 paper

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedMay 24, 2026

Pontocerebellar Hypoplasia linked mutations of the deadenylase Target of EGR1 (TOE1) impair thermal stability, ribonuclease activity, and oligomerization.

Lizette Zavala, Magdalena Sobień, Cassandra K. Hayne

This study investigates how PCH7-linked TOE1 mutations affect thermal stability, ribonuclease activity, and oligomerization, revealing their impact on TOE1 biochemistry.

1 citation

humanprotein structure

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