ImmunologyeLifePeer-reviewed
Unraveling the Role of Ctla-4 in Intestinal Immune Homeostasis: Insights from a novel Zebrafish Model of Inflammatory Bowel Disease
Lulu Qin, Chongbin Hu, Qiong Zhao…·Jian-zhong Shao
This study identifies a zebrafish model of IBD by knocking out Ctla-4, showing similar intestinal inflammation and immune dysregulation to mammalian IBD.