Cancer BiologybioRxivPreprint
Nanoparticle Metal Mass Uptake Governs Radiosensitizing Efficacy Across 2D, 3D, and In Vivo Models
Lukas R. H. Gerken, Laurin G.S. Schaller, Rüveyda Dok…·Inge Katrin Herrmann
This study develops a 3D spheroid model of head and neck cancer to evaluate nanoparticle radiosensitization across 2D, 3D, and in vivo settings, finding consistent effects when nanoparticle mass uptake is matched.
DOI 10.1101/2025.08.13.670090