Author

Hans G. H. J. Heilig

Wageningen University & ResearchORCID 0000-0002-5545-6713Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Barbara R. TerlouwiD· 1 shared Charlotte C. KosteriD· 1 shared John van der OOSTiD· 1 shared María Martín‐PascualiD· 1 shared Miguel Paredes-BarradaiD· 1 shared Nico J. ClaassensiD· 1 shared Panagiotis KopsiaftisiD· 1 shared Sjoerd C.A. CreutzburgiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Barbara R. TerlouwORCID

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1 paper

Recent·Most cited

Systematic engineering and machine learning analysis of intrinsic terminators reveal crucial nucleotides directly upstream of the terminator hairpin.

Charlotte C. Koster, Barbara R. Terlouw, Thijs Nieuwkoop, Sjoerd C.A. Creutzburg, María Martín‐Pascual, Miguel Paredes-Barrada, Panagiotis Kopsiaftis, Hans G. H. J. Heilig, Theo van Laar, John van der OOST, Nico J. Claassens

The paper systematically engineers and analyzes intrinsic terminators in bacteria, finding that an adenosine upstream of the terminator hairpin improves protein production and reduces read-through.

bioRxiv · Jul 7, 2026 · PreprintMolecular Biology