Author

Zhao Yan

KU LeuvenORCID 0000-0002-5546-705XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Greet Peeters· 2 shared Joris Robert VermeeschiD· 2 shared Olga TšuikoiD· 2 shared Tatjana JatsenkoiD· 2 shared Andrea Fernández-MontoroiD· 1 shared Ann Van SoomiD· 1 shared Ants KurgiD· 1 shared Arne Vanhie· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersGenetics

Greet Peeters

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2 papers

Recent·Most cited

Origin and development of uniparental and polyploid blastomeres

Zhao Yan, Andrea Fernández-Montoro, Greet Peeters, Tatjana Jatsenko, Tine De Coster, Daniel Angel‐Velez, Thomas Lefevre, Thierry Voet, Olga Tšuiko, Ants Kurg, Katrien Smits, Ann Van Soom, Joris Robert Vermeesch

The paper identifies mechanisms of whole-genome abnormal blastomere formation and their developmental outcomes in early embryos.

iScience · Apr 3, 2025Peer-reviewedGenetics

Long-read whole-genome sequencing-based concurrent haplotyping and aneuploidy profiling of single cells

Zhao Yan, Olga Tšuiko, Tatjana Jatsenko, Greet Peeters, Erika L. Souche, Mathilde Geysens, Eftychia Dimitriadou, Arne Vanhie, Karen Peeraer, Sophie Debrock, Hilde Van Esch, Joris Robert Vermeesch

This study demonstrates that long-read whole-genome sequencing can accurately haplotype and detect aneuploidies in single cells, offering an alternative to current preimplantation genetic testing methods.

Nucleic Acids Research · Mar 20, 2025Peer-reviewedGenomics