Tatjana Jatsenko

The paper analyzes cfDNA methylome and fragmentome profiles from healthy individuals to identify cell-type and demographic signatures influencing cfDNA characteristics.

The paper identifies mechanisms of whole-genome abnormal blastomere formation and their developmental outcomes in early embryos.

This study demonstrates that long-read whole-genome sequencing can accurately haplotype and detect aneuploidies in single cells, offering an alternative to current preimplantation genetic testing methods.

MetDecode uses methylation patterns to estimate tumor proportion and identify tissue origin in cell-free DNA samples from cancer patients.

This paper introduces an optimal transport-based domain adaptation method to correct technical biases in cfDNA sequencing data, improving cancer detection and enabling cohort integration.

The paper develops a method to detect and type cancer using cfDNA sequencing data, achieving 81.62% accuracy in distinguishing malignant from control samples.

TAC-seq is a targeted sequencing method using UMIs to count biomarker molecules, showing improved accuracy in mRNA, microRNA, and cell-free DNA analysis compared to standard sequencing.