Olga Tšuiko

The paper uses single-cell RNA-sequencing to analyze cervical and placental tissues, identifying a novel trophoblast subtype and revealing similarities between maternal epithelial cells and placental trophoblasts.

The paper identifies mechanisms of whole-genome abnormal blastomere formation and their developmental outcomes in early embryos.

This study demonstrates that long-read whole-genome sequencing can accurately haplotype and detect aneuploidies in single cells, offering an alternative to current preimplantation genetic testing methods.