NeurosciencebioRxivPreprint
Novel mouse model of cerebral microbleeds created by Crispr/Cas9-mediated Col4a1 deletion in adult brain microvessels
Hyunmi Kim, Yeojin Seo, Heekyung Kho…·Byung Gon Kim
This study creates a novel mouse model of cerebral microbleeds by deleting Col4a1 in adult brain microvessels, showing progressive CMB burden and cognitive decline.
DOI 10.1101/2025.06.22.660900