Jasmin Mecinović

This study uses multimodal mass spectrometry to accurately map co-occurring histone modifications on intact proteins, enabling residue-level assignment of modifications and positional isomers.

This paper evaluates ion mobility spectrometry for resolving isomeric acyl-lysine modifications on histone peptides, showing improved separation with cyclic IMS and revealing structure-mobility relationships.

The paper identifies novel biomarkers for pyridoxine-dependent epilepsy using metabolomics and infrared ion spectroscopy, showing their potential for newborn screening and clinical implications.