Author

Jona Merx

Radboud University NijmegenORCID 0000-0002-4451-4463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:metabolomics· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Organism:mouse· 1

Frequent Co-Authors

Thomas Jan BoltjeiD· 2 shared Arno van Rooij· 1 shared Bai HE ZhangiD· 1 shared Blair R. LeavittiD· 1 shared Clara van KarnebeekiD· 1 shared Eduard A. StruysiD· 1 shared Erik de VriezeiD· 1 shared Erwin van WijkiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

Thomas Jan BoltjeORCID

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2 papers

Recent·Most cited

A new stress-response pathway in Mycobacterium tuberculosis

Pieter M. M. van der Velden, Jona Merx, Lars van Dijk, Femke Roos, J. Brake, Tom Berben, Paul B. White, Rob M. de Graaf, Eva Terschlüsen, Ingrid J.M. van Weerdenburg, Bai HE Zhang, Reinout van Crevel, Laura van Niftrik, Jakko van Ingen, Thomas Jan Boltje, Robert S. Jansen

This study identifies a new stress-response pathway in Mycobacterium tuberculosis that produces GABA-trehalose under hypoxia and immune stress.

bioRxiv · Apr 16, 2026 · PreprintBiochemistry

Identification of novel biomarkers for pyridoxine-dependent epilepsy using untargeted metabolomics and infrared ion spectroscopy - biochemical insights and clinical implications

Udo F. H. Engelke, Rianne E. van Outersterp, Jona Merx, Fred A. M. G. van Geenen, Arno van Rooij, Giel Berden, Marleen C.D.G. Huigen, Leo A. J. Kluijtmans, Tessa M. A. Peters, Hilal H. Al-Shekaili, Blair R. Leavitt, Erik de Vrieze, Sanne Broekman, Erwin van Wijk, Laura A. Tseng, , Karlien L. M. Coene

The paper identifies novel biomarkers for pyridoxine-dependent epilepsy using metabolomics and infrared ion spectroscopy, showing their potential for newborn screening and clinical implications.

Journal of Clinical Investigation · Jun 17, 2021Peer-reviewedGenetic & Genomic Medicine