Author

Ksenia M. Klimina

Federal Research and Clinical Center of Physical-Chemical Medicine named after Y.M. LopukhinORCID 0000-0002-5563-644XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:metagenomics· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Approach:matrix factorization· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Fedoseeva· 1 shared A. G. VasilieviD· 1 shared A. MulyukinaiD· 1 shared A.V. Troitsky· 1 shared ALEXANDER A. TULICHEViD· 1 shared Alexander G. RumyantseviD· 1 shared Alexander I. ManoloviD· 1 shared Alexander Vladimirovich PavlenkoiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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1 shared paperSystems Biology

A. Fedoseeva

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TP63-TRIM29 axis regulate enhancer methylation and chromosomal instability in prostate cancer

Султанов Ринат Илгизович, A. Mulyukina, Olga A. Zubkova, A. Fedoseeva, Alexandra N. Bogomazova, Ksenia M. Klimina, Andrey K. Larin, Timofei S. Zatsepin, T. A. Prikazchikova, Maria M. Lukina, Margarita E. Bogomiakova, Elena Ivanovna Sharova, Edward V. Generozov, Maria A. Lagarkova, Georgij P. Arapidi

The paper identifies TP63 and TRIM29 as regulators of enhancer methylation and chromosomal instability in prostate cancer by integrating multi-omics data from The Cancer Genome Atlas.

Epigenetics & Chromatin · Mar 14, 2024Peer-reviewedSystems Biology

Systemic Metabolic Depletion of Intestine Microbiome Undermines Melanoma Immunotherapy Effectiveness

Natalia V. Zakharevich, Maxim D. Morozov, Vera A. Kanaeva, Artem B. Ivanov, Ульянцев Владимир Игоревич, Ksenia M. Klimina, Evgenii I. Olekhnovich

This study identifies that systemic metabolic depletion of the gut microbiome reduces immunotherapy effectiveness in melanoma by altering cobalamin and amino acid metabolism.

bioRxiv · Oct 9, 2023 · PreprintBioinformatics

Analysis of the upper respiratory tract microbiota in mild and severe COVID-19 patients

Vladislav V. Babenko, Ramiz Bakhtyev, Vladimir P. Baklaushev, Лариса Александровна Балыкова, Pavel V. Bashkirov, Julia Bespyatykh, Anna Sergeevna Blagonravova, Daria I. Boldyreva, D. Fedorov, Ilshat Gafurov, Raushania F. Gaifullina, Julia S. Galeeva, Елена Анатольевна Галова, Alina Gospodaryk, Elena Nikolaevna Ilina, , Vadim Markovich Govorun

The paper analyzes the respiratory tract microbiota in COVID-19 patients to find associations between microbiota composition and disease severity.

bioRxiv · Sep 20, 2021 · PreprintMolecular Biology