Author

David D. McKemy

University of Southern CaliforniaORCID 0000-0002-5583-5983Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Chenyu YangiD· 2 shared Brian Kim· 1 shared Chao WeiiD· 1 shared Ryan Huyhn· 1 shared Sanaa Alam· 1 shared Shanni Yamaki· 1 shared Tyler Jung· 1 shared Xunyang CheniD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersNeuroscience

Chenyu YangORCID

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2 papers

Recent·Most cited

The neurotrophic factor artemin and its receptor GFRα3 mediate migraine-like pain via the ion channel TRPM8

Chenyu Yang, Chao Wei, Sanaa Alam, Xunyang Chen, David D. McKemy

This study identifies artemin and its receptor GFRα3 as mediators of migraine-like pain via TRPM8 in mice, showing their role in neuroinflammatory processes in the meninges.

Cephalalgia · Nov 1, 2024Peer-reviewedNeuroscience

Endogenous inflammatory mediators produced by injury activate TRPV1 and TRPA1 nociceptors to induce sexually dimorphic cold pain that is dependent on TRPM8 and GFRalpha3

Chenyu Yang, Shanni Yamaki, Tyler Jung, Brian Kim, Ryan Huyhn, David D. McKemy

The paper shows that inflammatory mediators activate TRPV1 and TRPA1 nociceptors, leading to cold pain in mice that depends on TRPM8 and GFRalpha3, with sex-specific effects.

Journal of Neuroscience · Mar 10, 2023Peer-reviewedNeuroscience