Amruta D. S. Pathare

This paper uses AlphaGenome to prioritize endometriosis-associated variants with strong uterus-specific regulatory effects, identifying new candidate genes and refining GWAS loci.

This study investigates how microbial compounds D-lactate and LPS affect endometrial epithelial function using organoids, showing distinct gene expression changes related to growth and inflammation.

This study compares 16S rRNA gene sequencing and meta-transcriptomic analyses of endometrial microbiota, finding weak correlation in low-biomass environments and highlighting the value of RNA-based functional insights.

The paper investigates endometrial polyps using bulk and single-cell RNA sequencing, identifying aberrant stromal-to-epithelial transitions and altered differentiation trajectories.

The paper uses single-cell RNA-sequencing to identify distinct metabolic signatures in endometriotic lesions compared to eutopic endometrium, highlighting altered pathways and steroidogenesis-related genes in specific cell types.