BioinformaticsbioRxivPreprint
Evolutionary Decoding of the Bacillus subtilis Secretome: Insights from Pan-Genomics and Deep Learning
Chong Peng, Chengwu Yuan, Linhao Meng…·Yihan Liu
This study uses pan-genomics and deep learning to analyze signal peptides in 287 Bacillus subtilis strains, revealing an open pan-signal peptidome and evolutionary decoupling between signal peptides and mature proteins.
DOI 10.64898/2025.12.19.695619