Synteny-aware functional annotation of bacteriophage genomes with Phynteny
Susanna R. Grigson, George Spyro Bouras, Bhavya Nalagampalli Papudeshi…·Robert Alan Edwards
Phynteny combines ESM2 protein embeddings, a BiLSTM, and circular-attention transformer layers to exploit phage gene order, assigning one of nine PHROG functional categories to unannotated genes.