An integrated polygenic score stratifies risk of peripheral artery disease and adverse limb events in ancestrally diverse cohorts
Alyssa Monica Flores, Yunfeng Ruan, Anika Misra, Margaret Sunitha Selvaraj, Tiffany R. Bellomo, Tetsushi Nakao, Kenneth Rosenfield, Matthew Jeremiah Eagleton, Whitney Hornsby, Aniruddh P. Patel, Pradeep Natarajan
This paper develops a polygenic score for peripheral artery disease (PAD) that improves risk prediction across diverse populations and identifies high-risk individuals for adverse limb events.
medRxiv · Oct 4, 2024 · PreprintGenetic & Genomic Medicine