Matthew Jeremiah Eagleton

This study evaluates polygenic risk scores for cardiovascular diseases in predicting carotid stenosis, finding that PAD and CAD PRSs show significant associations and improved discrimination over traditional risk factors.

This study identifies FNDC1 as a key regulator of vascular calcification through the FNDC1-NAMPT-NAD axis, showing its role in both microvascular and macrovascular diseases and its potential as a therapeutic target.

This paper develops a polygenic score for peripheral artery disease (PAD) that improves risk prediction across diverse populations and identifies high-risk individuals for adverse limb events.