The effect of PEGylation on surface tethering of liposomes via DNA nanotechnology.
James P Gaston, Sreelakshmi Meppat, Md. Sirajul Islam, Jiahe Li, Jasleen Kaur Daljit Singh, Michael J. Booth, Shelley F. J. Wickham, Matthew A. B. Baker
This study investigates how varying PEG content in liposomes affects DNA-mediated surface tethering, finding that PEG can either block or enhance binding depending on membrane composition and PEG concentration.
Journal of Lipid Research · Nov 14, 2025Peer-reviewedBiophysics