Systems BiologybioRxivPreprint
Mathematical Models of Retinal Drug Delivery
Paul A. Roberts, Chloe N. Thomas, Gabriel Bellamy Plaice…·Lisa J. Hill
This study evaluates topical and intravitreal ranibizumab treatments for wet AMD using ex vivo pig eyes and mathematical modeling, finding topical treatment can sustain moderate VEGF suppression while intravitreal provides stronger but less consistent effects.
DOI 10.1101/2024.12.17.629033