Paul Roberts

The paper demonstrates that lactate produced by rod photoreceptors supports cone photoreceptor function and viability through a rod-to-cone lactate shuttle, suggesting new therapeutic avenues for retinal diseases.

This study evaluates topical and intravitreal ranibizumab treatments for wet AMD using ex vivo pig eyes and mathematical modeling, finding topical treatment can sustain moderate VEGF suppression while intravitreal provides stronger but less consistent effects.

The paper shows that birds use a different retinal circuit strategy compared to mammals, with On- and Off-circuits encoding visual information in a correlated manner rather than as opposing channels.

The paper formulates a mathematical model of retinitis pigmentosa to derive experimentally testable conditions for the trophic factor hypothesis to replicate observed retinal degeneration patterns.

This study investigates how amacrine cells in zebrafish retinas differentially balance colour and greyscale processing in central and peripheral regions through distinct inhibitory circuits.

This paper develops mathematical models under the trophic factor hypothesis to predict cone degeneration in retinitis pigmentosa following rod loss.

The paper characterizes retinal ganglion cells (RGCs) in larval zebrafish, revealing UV-responsive RGCs and complex color opponency, suggesting a dual-achromatic visual strategy for prey capture and color vision.