James A. Roberts

This study uses cross-omics analysis in a neonatal mouse model of IVH to identify cortical neuronal dysfunction and shows decorin treatment reduces injury by targeting ferroptosis and enhancing microglial phagocytosis.

This study shows that CDDO-Me activates NRF2 to protect AC16 human cardiomyocytes from doxorubicin-induced toxicity by modulating p53 signaling, apoptosis, and ferroptosis.

This paper introduces an adult rat organotypic brain slice culture model to study ECM remodelling in haemorrhagic stroke and shows increased ECM deposition and inflammation after blood exposure.

This study evaluates topical and intravitreal ranibizumab treatments for wet AMD using ex vivo pig eyes and mathematical modeling, finding topical treatment can sustain moderate VEGF suppression while intravitreal provides stronger but less consistent effects.