ImmunologybioRxivPreprint
Genetic and environmental imprints on T cell receptor repertoires as predictors of graft-versus-host disease
Assya Trofimov, Zachary Montague, Magdalena L Russell…·Armita Nourmohammad
This study shows that donor T cell receptor repertoires are influenced by both HLA genetics and recent viral infections, with higher HLA heterozygosity and TCR-HLA coherence linked to increased GVHD risk.
DOI 10.64898/2025.12.23.696252