Cancer BiologyMolecular CancerPeer-reviewed
Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment
Christina Sternberg, Martin Raigel, Tanja Limberger…·Lukas Kenner
This study shows that activating GP130 in prostate epithelial cells suppresses tumor growth through senescence and immune activation, suggesting a new therapeutic approach.
17 citations