Author

Jan Pěnčík

Medical University of ViennaORCID 0000-0002-6299-1749Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Boris TichýiD· 1 shared Christina SternbergiD· 1 shared Daniela ZwolanekiD· 1 shared Desiree Lindner· 1 shared Felix SternbergiD· 1 shared Gerda EggeriD· 1 shared Heidi Anne NeubaueriD· 1 shared Jenny Liao PerssoniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Boris TichýORCID

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1 paper

Recent·Most cited

Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment

Christina Sternberg, Martin Raigel, Tanja Limberger, Karolína Trachtová, Michaela Schlederer, Desiree Lindner, Petra Kodajova, Jiaye Yang, Roman Ziegler, Jessica Kalla, Stefan Stoiber, Saptaswa Dey, Daniela Zwolanek, Heidi Anne Neubauer, Monika Oberhuber, , Lukas Kenner

This study shows that activating GP130 in prostate epithelial cells suppresses tumor growth through senescence and immune activation, suggesting a new therapeutic approach.

Molecular Cancer · Oct 31, 2024Peer-reviewedCancer Biology