Author

Madeleine S. Gastonguay

Jackson LaboratoryORCID 0000-0002-5700-8543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Gary A. ChurchilliD· 2 shared Gregory R. KeeleiD· 2 shared Wesley L. CrouseiD· 1 shared William S. J. ValdariD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersGenetics

Gary A. ChurchillORCID

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2 papers

Recent·Most cited

GeneticsGeneticsPeer-reviewedMar 18, 2023

The Trouble with Triples: Examining the Impact of Measurement Error in Mediation Analysis

Madeleine S. Gastonguay, Gregory R. Keele, Gary A. Churchill

This paper shows that measurement error in mediation analysis can lead to incorrect causal inferences in genetic studies, even when no true mediation exists.

2 citations

statistical model

𝕏 PostBluesky

GeneticsPLoS GeneticsPeer-reviewedMay 9, 2022

A Bayesian model selection approach to mediation analysis

Wesley L. Crouse, Gregory R. Keele, Madeleine S. Gastonguay…·William S. J. Valdar

The paper introduces a Bayesian model selection approach for mediation analysis and demonstrates its effectiveness using genetic data from mice and human cell lines.

31 citations

𝕏 PostBluesky