Enterovirus D68 infection of human inducible pluripotent stem cell-derived skeletal muscles resulted in structural destruction, loss of muscle function and hampered muscle regeneration
Brigitta M. Laksono, Atze J. Bergsma, Alessandro Iuliano, Dominique Y. Veldhoen, Stefan van Nieuwkoop, Marjan Boter, Lonneke M. E. Leijten, Lisa Bauer, Bas B. Oude Munnink, W.W.M. Pim Pijnappel, Debby A.J. van Riel
This study shows EV-D68 infects human skeletal muscles, causing structural damage, loss of function, and impaired regeneration.
bioRxiv · Apr 7, 2025 · PreprintMicrobiology