Dominic R. W. Burrows

This study uses spatial transcriptomics to show that Alzheimer's disease disrupts circadian rhythms in specific brain regions before amyloid plaques form in a mouse model.

The paper studies neuronal dynamics in larval zebrafish during development, finding region-specific balance between stability and flexibility, with the telencephalon showing increased stability and long-term attractor dynamics.

The paper shows that EI imbalance during seizures disrupts whole-brain critical dynamics by reorganizing neural networks, leading to chaotic and less stable brain states.