Author

Andrea Frustaci

Istituto Nazionale per le Malattie Infettive Lazzaro SpallanzaniORCID 0000-0002-5748-0725Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Cristina ChimentiiD· 1 shared Emanuela Frustaci· 1 shared Matteo Antonio RussoiD· 1 shared Michele MagnocavalloiD· 1 shared Romina VerardoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperPathology

Cristina ChimentiORCID

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1 paper

Recent·Most cited

PathologyJournal of the American Heart AssociationPeer-reviewedFeb 8, 2025

Fabry Cardiomyopathy: Myocardial Fibrosis, Inflammation and Down-Regulation of Mannose-6-Phosphate Receptors cause Low accessibility to Enzyme Replacement Therapy

Andrea Frustaci, Romina Verardo, Michele Magnocavallo…·Cristina Chimenti

This study investigates the limited effectiveness of enzyme replacement therapy (ERT) in advanced Fabry disease cardiomyopathy, identifying myocardial fibrosis, inflammation, and reduced mannose-6-phosphate receptors as barriers to therapy.

7 citationstop 4%

humanimaging

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